Acute Lymphoblastic Leukemia: Introduction
نویسندگان
چکیده
منابع مشابه
Bone Scintigraphy in Acute Lymphoblastic Leukemia
Leukemia is the most common childhood cancer and accounts for 30-40% of all malignancies. A retrospective review was performed of the hospital records of 9 children, 6 boys and 3 girls, aged from 2.5 to 15 years with ALL initially referred to Nemazee hospital Nuclear medicine center for whole body bone scanning between 2000 and 2002. Bone marrow pathology established ALL (L1) in two and ALL (...
متن کاملAcute Lymphoblastic Leukemia
Key-words Definition/Diagnostic criteria Pathogenesis Clinical Presentation Diagnostic methods Epidemiology Treatment Relapse of acute lymphoblastic leukemia References Abstract Acute lymphoblastic leukemia (ALL) is a malignant proliferation of lymphoid cells blocked at an early stage of differentiation and accounts for 3⁄4 of all cases of childhood leukaemia. About 3,000 children in the United...
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Results ETV6/RUNX1 had a strong effect on overall survival after relapse (3-year survival= 64.7% for positive cases versus 46.5% for negative cases) (P=0.007). The 5-year cumulative incidence of relapse was 19.4% and testes were more frequently involved in ETV6/RUNX1-positive relapses (P=0.04). In 81.4% of cases the relapses were late, early combined or isolated extramedullary relapses. The 5-y...
متن کاملAcute lymphoblastic leukemia.
Acute lymphoblastic leukemia and lymphoblastic lymphoma constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms. Current intensive chemotherapy regimens have acc...
متن کاملSignificance of Cross Lineage Antigen Expression in Acute Lymphoblastic Leukemia
Background: Aberrant expression of cross-lineage antigens gives valuable insight into the diagnosis and prognosis of acute leukemia. In countries like India, cytogenetic tests are widely accessible. Exploring the prognostic value of an accessible test is of great importance. Therefore, establishing a population-specific immunophenotype database will enable to design an antibody panel equipped t...
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ژورنال
عنوان ژورنال: Seminars in Hematology
سال: 2009
ISSN: 0037-1963
DOI: 10.1053/j.seminhematol.2008.09.011